„MDM2-P53 interaction“
Suchergebnisse
1.000+ Treffer
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Interaction between p53 codon 72 and MDM2 309T>G polymorphisms and the risk of hepatocellular carcinoma
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Front Cover: Discovery of SCY45, a Natural Small‐Molecule MDM2‐p53 Interaction Inhibitor (C&B 6/2019)
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A Left‐Handed Solution to Peptide Inhibition of the p53–MDM2 Interaction †
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A Left‐Handed Solution to Peptide Inhibition of the p53–MDM2 Interaction †
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High Specificity in Protein Recognition by Hydrogen‐Bond‐Surrogate α‐Helices: Selective Inhibition of the p53/MDM2 Complex
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Native PAGE to study the interaction between the oncosuppressor p53 and its protein ligands
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Probing the Small‐Molecule Inhibition of an Anticancer Therapeutic Protein‐Protein Interaction Using a Solid‐State Nanopore
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Probing the Small‐Molecule Inhibition of an Anticancer Therapeutic Protein‐Protein Interaction Using a Solid‐State Nanopore
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Bioorthogonal Probes for the Study of MDM2‐p53 Inhibitors in Cells and Development of High‐Content Screening Assays for Drug Discovery
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Targeted Synthesis of Complex Spiro (3 H ‐indole‐3,2′‐pyrrolidin)‐2 (1 H)‐ones by Intramolecular Cyclization of Azomethine Ylides: Highly Potent MDM2–p53 Inhibitors
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Discovery of 1,2‐Naphthoquinone Derivatives as Potent p53‐MDM2 Interaction Inhibitors
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Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions
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Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions
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Inhibitors of the p53-Mdm2 interaction increase programmed cell death and produce abnormal phenotypes in the placozoon Trichoplax adhaerens (F.E. Schulze)
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Targeting the p53-MDM2 and p53-MDMX interaction as a therapeutic strategy for anticancer treatment
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NMR high resolution spectroscopy and X-ray crystallography for development of MDM2/X-p53 interaction antagonists
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Small-Molecule Inhibitors of p53-MDM2 interactions
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Small-molecule inhibitors of cyclin-dependent kinase 2 (CDK2) and the p53-Mdm2 interaction
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Nutlin-3a-aa – Improving the Bioactivity of a p53/MDM2 Interaction Inhibitor by Introducing a Solvent-Exposed Methylene Group
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Discovery of Furopyrimidine‐Pyrazole Hybrid Compounds Targeting p53‐MDM2 Interaction as Anticancer Agents