Suchergebnisse: Blockade

1,25(OH)2D3 and dexamethasone additively suppress synovial fibroblast activation by CCR6+ T helper memory cells and enhance the effect of tumor necrosis factor alpha blockade

Dankers, Wendy ; González-Leal, Claudia ; Davelaar, Nadine ; Asmawidjaja, Patrick S. ; Mus, Adriana M. C. ; Hazes, Johanna M. W. ; Colin, Edgar M. ; Lubberts, Erik

A whole-blood RNA transcript-based gene signature is associated with the development of CTLA-4 blockade-related diarrhea in patients with advanced melanoma treated with the checkpoint inhibitor tremelimumab

Friedlander, Philip ; Wood, Kevin ; Wassmann, Karl ; Christenfeld, Alan M. ; Bhardwaj, Nina ; Oh, William K.

T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis

Boleto, Gonçalo ; Guignabert, Christophe ; Pezet, Sonia ; Cauvet, Anne ; Sadoine, Jérémy ; Tu, Ly ; Nicco, Carole ; Gobeaux, Camille ; Batteux, Frédéric ; Allanore, Yannick ; Avouac, Jérôme

Combinatorial immunotherapy of sorafenib and blockade of programmed death-ligand 1 induces effective natural killer cell responses against hepatocellular carcinoma

Wang, Yun ; Li, Hongxia ; Liang, Qi ; Liu, Bin ; Mei, Xiaqi ; Ma, Yingji

Change in neutrophil-to-lymphocyte ratio (NLR) in response to immune checkpoint blockade for metastatic renal cell carcinoma

Lalani, Aly-Khan A. ; Xie, Wanling ; Martini, Dylan J. ; Steinharter, John A. ; Norton, Craig K. ; Krajewski, Katherine M. ; Duquette, Audrey ; Bossé, Dominick ; Bellmunt, Joaquim ; Allen, Eliezer M. van ; McGregor, Bradley A. ; Creighton, Chad J. ; Harshman, Lauren C. ; Choueiri, Toni K.

PD-1 blockade in combination with zoledronic acid to enhance the antitumor efficacy in the breast cancer mouse model

Li, Yuan ; Du, Yang ; Sun, Ting ; Xue, Huadan ; Jin, Zhengyu ; Tian, Jie

Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis

Jin, Kideok ; Pandey, Niranjan B. ; Popel, Aleksander S.

Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade

Holmgaard, Rikke B. ; Schaer, David A. ; Li, Yanxia ; Castaneda, Stephen P. ; Murphy, Mary Y. ; Xu, Xiaohong ; Inigo, Ivan ; Dobkin, Julie ; Manro, Jason R. ; Iversen, Philip W. ; Surguladze, David ; Hall, Gerald E. ; Novosiadly, Ruslan D. ; Benhadji, Karim A. ; Plowman, Gregory D. ; Kalos, Michael ; Driscoll, Kyla E.

Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer

Ribas, Ricardo ; Pancholi, Sunil ; Rani, Aradhana ; Schuster, Eugene ; Guest, Stephanie K. ; Nikitorowicz-Buniak, Joanna ; Simigdala, Nikiana ; Thornhill, Allan ; Avogadri-Connors, Francesca ; Cutler, Richard E. ; Lalani, Alshad S. ; Dowsett, Mitch ; Johnston, Stephen R. ; Martin, Lesley-Ann

Usefulness of combined androgen blockade therapy with gonadotropin-releasing hormone antagonist for bone metastatic prostate cancer with pretreatment prostate-specific antigen level ≥ 50 ng/mL

Kashiwabara, Takeshi ; Suda, Sayo

Influenza vaccination of cancer patients during PD-1 blockade induces serological protection but may raise the risk for immune-related adverse events

Läubli, Heinz ; Balmelli, Catharina ; Kaufmann, Lukas ; Stanczak, Michal ; Syedbasha, Mohammedyaseen ; Vogt, Dominik ; Hertig, Astrid ; Müller, Beat ; Gautschi, Oliver ; Stenner, Frank ; Zippelius, Alfred ; Egli, Adrian ; Rothschild, Sacha I.

IL-6 blockade in systemic juvenile idiopathic arthritis – achievement of inactive disease and remission (data from the German AID-registry)

Bielak, M. ; Husmann, E. ; Weyandt, N. ; Haas, J.-P ; Hügle, B. ; Horneff, G. ; Neudorf, U. ; Lutz, T. ; Lilienthal, E. ; Kallinich, T. ; Tenbrock, K. ; Berendes, R. ; Niehues, T. ; Wittkowski, H. ; Weißbarth-Riedel, E. ; Heubner, G. ; Oommen, P. ; Klotsche, J. ; Foell, Dirk ; Lainka, E.

CCL17 blockade as a therapy for osteoarthritis pain and disease

Lee, Ming-Chin ; Saleh, Reem ; Achuthan, Adrian ; Fleetwood, Andrew J. ; Förster, Irmgard ; Hamilton, John A. ; Cook, Andrew D.

The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey

Jeyaratnam, Jerold ; ter Haar, Nienke M. ; Lachmann, Helen J. ; Kasapcopur, Ozgur ; Ombrello, Amanda K. ; Rigante, Donato ; Dedeoglu, Fatma ; Baris, Ezgi H. ; Vastert, Sebastiaan J. ; Wulffraat, Nico M. ; Frenkel, Joost

Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis

Luong, Vu Huy ; Chino, Takenao ; Oyama, Noritaka ; Matsushita, Takashi ; Sasaki, Yoko ; Ogura, Dai ; Niwa, Shin-ichiro ; Biswas, Tanima ; Hamasaki, Akiyuki ; Fujita, Mikako ; Okamoto, Yoshinari ; Otsuka, Masami ; Ihn, Hironobu ; Hasegawa, Minoru

Der Einfluss von Clonidin auf Blockadeausbreitung, Anästhesie- und Analgesiedauer bei der axillären Plexus-brachialis-Anästhesie

Ott, Bernhard